receptor
(rus. рецептор)
—
molecular or cellular structure receiving extrinsic and intrinsic stimuli and converting them into chemical or electrical signals to trigger biological response.
Description
There are physiological receptors and receptors specific to physiologically active substances.
Physiological receptors provide adaptation to the external environment (exteroreceptors) and constancy of the internal environment (interoreceptors).
Receptors of physiologically active substances are macromolecular biostructures with flexible conformation. specific binding Physiologically active substances induce their intrinsic effects through specific binding to their receptors. Interoreceptors can be located on cell membrane, being integrated / embedded into it (membrane receptors) or reside in cell cytoplasm (cytoplasmic receptors). An important condition for receptors to function is structural correspondence between receptors and the molecules that affect them. Their specific binding initiates a chain of events providing further determined changes in metabolism.
Physiological receptors provide adaptation to the external environment (exteroreceptors) and constancy of the internal environment (interoreceptors).
Receptors of physiologically active substances are macromolecular biostructures with flexible conformation. specific binding Physiologically active substances induce their intrinsic effects through specific binding to their receptors. Interoreceptors can be located on cell membrane, being integrated / embedded into it (membrane receptors) or reside in cell cytoplasm (cytoplasmic receptors). An important condition for receptors to function is structural correspondence between receptors and the molecules that affect them. Their specific binding initiates a chain of events providing further determined changes in metabolism.
Authors
- Ilya N. Kurochkin
- Alexander V. Maksimenko
Source
- Sergeev et al. Receptors of Physiologically Active Substances. — Moscow.: Medicina, 1987. — 400 pp.