oligonucleotide
(rus. олигонуклеотид)
— a short nucleotide chain of up to 20-30 bases.
Description
Nucleotides are components of nucleic acids consisting of a nitrogenous base, carbohydrate residue and a phosphate group. Short and long nucleotide sequences (polynucleotides) have no specific quantitative boundary; their classification is rather relative. Synthetic oligonucleotides (primers, probes, etc.) are widely used in molecular biology, genetic engineering and biotechnology, as well as for molecular diagnostics in medicine.
Authors
- Naroditsky Boris S.
- Shirinsky Vladimir P.
- Nesterenko Lyudmila N.
Sources
- B. Glick, J. Pasternak. Molecular Biotechnology: Principles and Applications of Recombinant DNA. — 3rd ed. Sigma Publishing, 2003, 784 pp.
- Jan Koolman, Klaus-Heinrich Rohm, Taschenatlas der Biochemie. 207 Farbtafeln von Jurgen Wirth 2., uberarbeitete und erweiterte Auflage 1998 Georg Thieme Verlag Stuttgart, New York.
