surface-supported membrane (rus. мембрана на подложке, липидная) — lipid bilayer stabilised by a solid surface; serves as a model of biological membranes and has found wide application in biotechnology.


A lipid bilayer can be deposited onto a solid surface, such as quartz, mica, gold, titanium oxide and other materials. A solid surface provides high stability to the membrane. The membrane is decoupled from the solid surface by a 1-2 nm thin aqueous layer that preserves the natural fluidity of the membrane. Surface-supported membranes have scientific and practical importance. In particular, they serve as a convenient model for studying processes in the vicinity of the nanoscale membrane, for example, using atomic force microscopy, or the phenomenon of surface plasmon resonance. From a practical point of view, these membranes can be used in analytical and diagnostic sensors, microchips and microfluidic devices. Their main utilisation qualities include selective permeability, biocompatibility and structural function (for example, membranes are widely used as carriers of transmembrane proteins).


  • Borisenko Grigory G.


  1. Castellana E. T., Cremer P. S. Solid supported lipid bilayers: From biophysical studies to sensor design // Surface Science Reports. 2006. V. 61. P. 429–444.

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