plasmid (rus. плазмида otherwise внехромосомный генетический элемент) — a small circular DNA molecule capable of replicating independently of the genome.

Description

Plasmids are usually found in the cells of bacteria and yeast. A typical plasmid is a double-stranded circular DNA molecule of 1–2 · 105 base pairs. Modified plasmids are widely used in genetic engineering as vectors for DNA cloning and in gene therapy for gene delivery into the cells.

Authors

  • Kurochkin Ilya N.
  • Shirinsky Vladimir P.

Sources

  1. Alberts B., Johnson A., Lewis J. et al. Molecular Biology of the Cell. 4th ed. — N.Y.: Garland Publishing, 2002. — 265 pp.
  2. B. Glick, J. Pasternak. Molecular Biotechnology: Principles and Applications of Recombinant DNA. — 3rd ed. Sigma Publishing, 2003, 784 pp.

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