oligonucleotide (rus. олигонуклеотид) — a short nucleotide chain of up to 20-30 bases.

Description

Nucleotides are components of nucleic acids consisting of a nitrogenous base, carbohydrate residue and a phosphate group. Short and long nucleotide sequences (polynucleotides) have no specific quantitative boundary; their classification is rather relative. Synthetic oligonucleotides (primers, probes, etc.) are widely used in molecular biology, genetic engineering and biotechnology, as well as for molecular diagnostics in medicine.

Authors

  • Naroditsky Boris S.
  • Shirinsky Vladimir P.
  • Nesterenko Lyudmila N.

Sources

  1. B. Glick, J. Pasternak. Molecular Biotechnology: Principles and Applications of Recombinant DNA. — 3rd ed. Sigma Publishing, 2003, 784 pp.
  2. Jan Koolman, Klaus-Heinrich Rohm, Taschenatlas der Biochemie. 207 Farbtafeln von Jurgen Wirth 2., uberarbeitete und erweiterte Auflage 1998 Georg Thieme Verlag Stuttgart, New York.

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